Vol 1, No 1

Table of Contents

Articles

Antimicrobial Activity of Some Medicinal Plants against Multi Drug Resistant Human Pathogens PDF
Al Nayem Chowdhury, M. Ashrafuzzaman, Hazrat Ali, Lutfun Nahar Liza, Kazi Mohammad Ali Zinnah

The present study was conducted with a view to evaluate the therapeutic potentials of twenty six plant extracts traditionally used in Bangladesh against human pathogenic bacteria Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis by disc diffusion method. Out of twenty six plant extracts eight crude plant extracts namely Allamanda cathartica (leaf), Allium sativum (bulb), Citrus limon (fruit), Tamarindus indica (fruit), Prunus domestica (Fruit), Averrhoa carambola (fruit), Piper betle (leaf) and Terminalia arjuna (leaf) were found to exhibit potential antimicrobial properties against the isolated human clinical bacterial isolates whereas twelve plant extracts were failed to show any antibacterial activity against any of the isolates of Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa followed by ten plant species in case of Proteus mirabilis. The maximum antimicrobial activity was found up to 80% in Tamarindus indica in case of Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis isolates meanwhile it is Averrhoa carambola which exhibited maximum activity against Escherichia coli isolates. Among the plant species tested, Tamarindus indica showed the most promising result. These results demonstrate the antimicrobial potential of the plants and hence lend support for the use of them in traditional medicine. Sensitivity of the bacterial isolates was also evaluated for eight commercial antibiotic discs where most of the isolates found to develop resistance against multiple commercial antibiotics. Among the antibiotics used, ciprofloxacin was the most effective one.

Further Observations on the Effects of Fast Neutron Irradiation on Morphological and Yield Traits of M1 and M2 Generation of African Wrinkled Pepper (Capsicum annuum var abbreviatum Fingerh) PDF
Falusi O. A, Daudu, O. A. Y, Thomas T, Mohammed, D. C Muhammad, L. M.
The mutagenic effects of fast Neutron irradiation (FNI) from an Am-Be source with a flux of 1.5 × 104 n cm-2 s-1, on the morphological and yield traits of M1 and M2 (M = filial mutant) generation of African Wrinkled Pepper(Capsicum annuum var abbreviatum Fingerh) were studied. Seeds of the pepper variety were irradiated for 0, 30, 60, 90 and 120 min before they were sown –with their respective controls – in order to assess the effects of the different irradiation treatments on the M1 and M2 generations of the pepper plants. Results showed both negative and positive shifts of characters as a result of FNI treatments. However, 60 minutes was observed to be the most effective IEP to induce viable and useful mutations for yield parameters in the pepper plants.

Influence of Sago Effluent on the Levels of the Enzyme Cholinesterase in the Brain Tissue of the Fresh Water Fish Clarias Batrachus PDF
Ramesh. F, Nagarajan. K
Monitoring of Cholinesterase activity has been widely used in aquatic and terrestrial systems as an indicator of pollutant exposure. The reports regarding impact of sago industry effluent on the level of ChE activity are very scanty. In this paper, an attempt has been made to investigate the in vitro impact of sago industry effluent upon the levels of ChE activity in the brain tissues of the fresh water fish, Clarias batrachus. The concentration chosen were 25%, 50% and 75% of treated sago effluent. The levels of ChE were decreased with increase in concentrations of the effluent. The control group recorded 268 u/l whereas the experimental groups such as 25%, 50% and 75% treated sago effluent showed 199u/l, 132u/l and 117u/l respectively.



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